Methylation profile analysis is a powerful method of molecular analysis, to improve the classification of brain and CNS tumors.
Protean utilizes the Illumina EPIC methylation arrays and special protocols developed by NIH to enable accurate analysis of the Epigenetic methylation pattern in DNA isolated from brain tumors.
FFPE materials can be utilized.
Over 900K of epigenetic methylation sites are measured and utilized in analysis by the NIH methylation classifier system.
This system produces accurate CNS tumor classification into over 100 subtypes of CNS tumors.
Accurate CNS tumor classification is essential for appropriate diagnosis and treatment selection.
Recent reports indicate that use of the CNS classifier can improve diagnosis in more than half of CNS tumors
IDH1/2 analysis, chromosome array, MGMT promoter methylation
Full Brain MAPS would also include the clinical trial matching and virtual tumor boards, portals, data sharing, etc.
We might also discuss the 3D genonomics or NGS as extra testing for brain tumors also cure match.
To view a CNS Methylation Sample Report, please fill your information below:
