Methylation profile analysis is a powerful method of molecular analysis, that improves the classification of brain and CNS tumors.
An example of a copy number plot for a progressive left frontal tumor,
Accurate CNS tumor classification is essential for appropriate diagnosis and treatment selection, and recent reports indicate that use of the CNS classifier can improve diagnosis in more than half of CNS tumors.
Protean utilizes the Illumina EPIC methylation arrays and special protocols developed by NIH to enable accurate analysis of the Epigenetic methylation pattern in DNA isolated from brain tumors.
FFPE materials can be utilized
Over 900K of epigenetic methylation sites are measured and utilized in analysis by the NIH methylation classifier system
This system produces accurate CNS tumor classification into over 100 subtypes of CNS tumors
Improves diagnosis in >50% of CNS tumors
The full Protean MAPS™ system for brain/CNS includes the clinical trial matching and virtual tumor boards, portals, data sharing, and more.
To view a CNS Methylation Sample Report, please fill out your information below:
