African American Women With Breast Cancer Have Unique Molecular Features and Reduced Clinical Trial Enrollment
Authors: Genevra Magliocco, Roy Khalife, Anthony Magliocco
Journal: Cancer Epidemiology, Biomarkers & Prevention
Publisher: The American Association for Cancer Research
Abstract PO-099
Introduction: African American (AA) women have a lower incidence of breast cancer (BC), however experience higher rates of more aggressive subtypes, mortality, and worse outcomes compared to Caucasian (C) women. Data also points to disparities among treatment access and response in AA women. Most existing genetic research and clinical trials have been conducted with majority C women, thus our existing knowledge about molecular profiles and effective treatments may not be accurate for AA women. The aim of this study is to uncover the biological and social factors related to treatment that may be causing this disparity in BC outcomes between AA and C women.